Prof. HO, Megan Yi Ping
Associate Professor, Department of Biomedical Engineering, CUHK

Area of Expertise: Droplet Microfluidics, DNA Nanosensors, Single Cell Analysis, Disease Diagnostics ypho@cuhk.edu.hk
Tel: 3943 4340
Location: ERB1117

Lab webpage: http://www.bme.cuhk.edu.hk/ypho/

About

Megan Yi-Ping Ho is currently an Associate Professor in the Department of Biomedical Engineering at The Chinese University of Hong Kong. She received her B.S. and M.S. in Power Mechanical Engineering from National Tsing-Hua University, Taiwan. She received her Ph.D. in Mechanical Engineering from the Johns Hopkins University in USA. After her postdoctoral training with Duke University in USA, she received the Young Elite Researcher Award from the Danish Research Council for Independent Research and started her independent career in the Interdisciplinary Nanoscience Centre and the Department of Molecular Biology and Genetics at Aarhus University in Denmark. She is also a co-founder of two start-up companies situated in Demark, Zymonostics and vPCiR, focusing on enzyme-based diagnostics.

Professional Education and Training

2008 Ph.D. in Mechanical Engineering, The Johns Hopkins University, USA
2002 M.S. in Mechanical Engineering, National Tsing-Hua University, Taiwan
2000 B.S. in Mechanical Engineering, National Tsing-Hua University, Taiwan

Research Interest

Development of nanosensors and microfluidics as diagnostic tools to expand the capacity of disease detection and treatment evaluation.

Course Teaching in CUHK

BMEG2210 Orthopaedic Biomechanics and Musculoskeletal Injury (2017-Present)
BMEG4410 BioMEMS (2017-Present)
BMEG2011 Biomedical Engineering Laboratory and Hospital Experience (2017-2019)
BMEG 5610 Research Methods in Biomedical Engineering (2018-Present)
ENGG5601 Principles of Biomechanics and Biomaterials (2017-2019

Honors & Awards

Dean’s Exemplary Teaching Award, The Chinese University of Hong Kong, 2020
Sapere Aude DFF-Ung Eliteforsker Award, Danish Council for Independent Research, 2012
Jorge Heller Outstanding Paper Award, Journal of Controlled Release, Elsevier, USA, 2007

Selected Publications

Y. Wei#, G. Cheng#, H. P. Ho, K. T. Yong*, Y. P. Ho*, "Thermodynamic Perspectives on Liquid-Liquid Droplet Reactors for Biochemical Applications," Chemical Society Reviews, 49: 6555-6567, 2020 (#Equal Contribution).

J. F. C. Loo, H. P. Ho, S. K. Kong, T. H. Wang, Y. P. Ho*, "Technological Advances in Multiscale Analysis of Single Cells in Biomedicine," Advanced Biosystems, 3: 1900138, 2019.

M. H. Rahman, Q. Xiao, S. Zhao, F. Qu, C. Chang, and A. C. Wei, Y. P. Ho*, "Demarcating the Membrane Damage for the Extraction of Functional Mitochondria," Microsystems & Nanoengineering, 4 (1): 39, 2018.

X. Ma, M. L. Jepsen, A. Ivarsen, B. R. Knudsen, and Y. P. Ho*, "Molecular and Functional Assessment of Multicellular Cancer Spheroids Produced in Double Emulsions Enabled by Efficient Airway Resistance Based Selective Surface Treatment," Journal of Micromechanics and Microengineering, 27(9): 095014, 2017. (Highlights of 2017 JMM Collection)

E. L. Kristoffersen, A. Givskov, L. A. Jørgensen, P. W. Jensen, W. Byl, J. Ann, N. Osheroff, A. H. Andersen, M. Stougaard, B. R. Knudsen*, Y. P. Ho*, "Interlinked DNA nano-circles for measuring topoisomerase II activity at the level of single decatenation events," Nucleic Acids Research, 45 (13): 7855-7869, 2017.

M. L. Jepsen, C. Harmsen, A. A. Godbole, V. Nagaraja, B. R. Knudsen, Y. P. Ho*, "Specific Detection of the Cleavage Activity of Mycobacterial Enzymes using a Quantum Dots based DNA Nanosensor," Nanoscale, 8 (1): 358-364, 2016.

Y. L. Chiu, H. F. Chan, K. K. L. Phua, Y. Zhang, S. Juul, B. R. Knudsen, K. W. Leong*, Y. P. Ho*, "Synthesis of Fluorosurfactants for Emulsion-Based Biological Applications," ACS Nano, 8 (4): 3913-3920, 2014.