Core Faculty Members

Prof. LI Tiantian

Research Assistant Professor, Department of Biomedical Engineering, CUHK

E-mail: tiantianli@cuhk.edu.hk
Tel: 3943 5073
Location: SHB617

Li received her B.Eng. degree in Biopharmaceutics from Huazhong University of Science and Technology in 2019 and completed her Ph.D. in Life Science at The Hong Kong University of Science and Technology (HKUST) in 2024. Following her Ph.D., she worked as a Postdoctoral Fellow in the Division of Life Science at HKUST. In June 2025, she joined the Department of Biomedical Engineering (BME) at CUHK as a Research Assistant Professor. Her research focuses on developing innovative synthetic biology tools to visualize and manipulate cellular events for therapeutic applications and achieving tunable modulation of cellular signaling.

2024-2025 Postdoctoral Fellow, Division of Life Science, The Hong Kong University of Science and Technology

2021-2024 Ph.D. in Life Science, Division of Life Science, The Hong Kong University of Science and Technology

2019-2021 MPhil in Life Science, Division of Life Science, The Hong Kong University of Science and Technology

2015-2019 B.Eng. in Biopharmaceutics, Huazhong University of Science and Technology

Develop tunable tools to modulate cell signaling for therapeutic breakthroughs.

Pioneer advanced visualization techniques to uncover novel cellular events.

Design non-invasive, targeted systems for drug delivery and gene therapy.

2021-2024 Hong Kong PhD Fellowship Award
2023&2024 Scholarship for academic and research excellence
2016&2017 National Encouragement Scholarship

1. Wang, X. ‡, Li, T. ‡, Guo, Y., Chen, X. (2025). License to drive: Receptor-mediated ER exit of proteins and lipids. Current Opinion in Cell Biology, Volume 94, 2025, 102501.

2. Li, T. ‡, Yang, F. ‡, Heng, Y., Zhou, S., Wang, G., Wang, J., Wang, J., Chen, X., Yao, Z. P., Wu, Z., Guo, Y. (2023). TMED10 mediates the trafficking of insulin-like growth factor 2 along the secretory pathway for myoblast differentiation. Proceedings of the National Academy of Sciences of the United States of America, 120(46), e2215285120. ‡, the authors contributed equally to this work.

3. Chen, R., Tang, X., Zhao, Y., Shen, Z., Zhang, M., Shen, Y., Li, T., Chung, C. H. Y., Zhang, L., Wang, J., Cui, B., Fei, P., Guo, Y., Du, S., Yao, S. (2023). Single-frame deep-learning super-resolution microscopy for intracellular dynamics imaging. Nature Communications, 2023 14:1, 14(1), 1–17.

4. Li, T., Guo, Y. (2022). ADP-Ribosylation Factor Family of Small GTP-Binding Proteins: Their Membrane Recruitment, Activation, Crosstalk and Functions. Frontiers in Cell and Developmental Biology, 10, 813353.

5. Yang, F., Li, T., Peng, Z., Liu, Y., Guo, Y. (2020). The amphipathic helices of Arfrp1 and Arl14 are sufficient to determine subcellular localizations. Journal of Biological Chemistry, 295(49), 16643–16654.

6. Li, Y., Wu, Y., Chen, J., Wan, J., Xiao, C., Guan, J., Song, X., Li, S., Zhang, M., Cui, H., Li, T., Yang, X., Li, Z., & Yang, X. (2019). A Simple Glutathione-Responsive Turn-On Theranostic Nanoparticle for Dual-Modal Imaging and Chemo-Photothermal Combination Therapy. Nano Letters, 19(8), 5806–5817.