Arthur Fuk-Tat Mak

Adjunct Professor, Biomedical Engineering



Book Chapters: 14 Google Scholar (10 July 2017)
Patents (Granted/ Filed): 5/8 Citation indices All Since 2012
Publications in SCI Journals: 140 Citations 7059 2523
Conference Presentations: 230 h-index 49 28
Invited Lectures: 85 i10-index 109 73

Selected Research Publications in the Last 5 Years:

  • DUAN XX, Mak AFT, WAN JMF. Oxidative Stress Alters the Morphological Responses of Myoblasts to Single-site Membrane Photoporation. Paper Accepted. Cellular and Molecular Bioengineering. DOI: 10.1007/s12195-017-0488-5. 26 April 2017.
  • WONG SW, CHEUNG BCH, PENG BTK, KWONG A, CHUNG A, LEE KKH, MAK AFT. Intermittent Vibration Protects Aged Muscle from Mechanical and Oxidative Damage under Prolonged Compression. J Biomechanics. 55(11): 113-120. April 2017.
  • WONG SW, YAO YF, Hong Y, MA ZY, KOK SHL, SUN S, CHO M, LEE KKH, MAK AFT. Preventive effects of poloxamer 188 on muscle cell damage mechanics under oxidative stress. 45(4):1083–1092. Annals of Biomedical Engineering. April 2017.
  • YAO YF, ONG LXD, LI XT, WAN KL, MAK AFT. Effects of Biowastes Released by Mechanically Damaged Muscle Cells on the Propagation of Deep Tissue Injury: A Multiphysics Study. Annals of Biomedical Engineering. 45(3):761–774. March 2017.
  • YAO YF, MAK AFT. Strengthening of C2C12 mouse myoblasts against compression damage by mild cyclic compressive stimulation. J Biomechanics, 49(16):3956-3961. December 2016.
  • YAO YF, LACROIX D, MAK AFT. Effects of oxidative stress-induced changes in the actin cytoskeletal structure on myoblast damage under compressive stress: confocal-based cell-specific finite element analysis. Biomechanics and Modeling in Mechanobiology. 15 (6):1495–1508. December 2016.
  • LAU EOC, LO CY, YAO YF, MAK AFT, JIANG L, HUANG Y, YAO XQ. Aortic Baroreceptors Display Higher Mechanosensitivity then Carotid Baroreceptors. Frontiers in Physiology, 7:384. 31 August 2016. DOI: 10.3389/fphys.2016.00384.
  • HONG Y, YAO YF, WONG SW, BIAN LM, MAK AFT. Change in viability of C2C12 myoblasts under compression, shear and oxidative challenges. Journal of Biomechanics, 49: 1305-1310, 2016.
  • MA ZL, WU YQS, MAK AFT. Rheological Behavior of Actin Stress Fibers in Myoblasts after Nanodissection: Effects of Oxidative Stress. Biorheology. 52:225-234. 2015.
  • DUAN XX, CHAN KT, LEE KKH, MAK AFT. Oxidative Stress and Plasma Membrane Repair in Single Myoblasts after Femtosecond Laser Photoporation. Annals of Biomedical Engineering. 43(11): 2735-2744, 2015.
  • WONG SW, SUN S, CHO M, LEE KKH, MAK AFT. H2O2 Exposure Affects Myotube Stiffness and Actin Filament Polymerization. Annals of Biomedical Engineering. 43(5):1178-1188. 2015.
  • YAO YF, XIAO ZT, WONG SW, HSU YC, CHENG T, CHANG CC, BIAN LM, MAK AFT. The Effects of Oxidative Stress on the Compressive Damage Thresholds of C2C12 Mouse Myoblasts: Implications for Deep Tissue Injury. Annals of Biomedical Engineering. 43(2): 287-296. 2015.
  • SUN S, WONG SW, MAK AFT, CHO M. Impact of Oxidative Stress on Cellular Biomechanics and Rho Signaling in C2C12 Myoblasts. Journal of Biomechanics, 47(2014): 3650-3656. 2014.
  • BIAN LM, MAK AFT, WU C, CHENG CYJ, GU ZW, ZHANG XD, QIN L. A Model for Facilitating Translational Research and Development in China: Call for Establishing a Hong Kong Branch of the Chinese National Engineering Research Centre for Biomaterials. Journal of Orthopaedic Translation. 2: 170-176. 2014.
  • XIAO ZT, WU YQ, MAK AFT. Accumulation of Loading and Unloading Reperfusion Injury – Modeling for the Propagation of Deep Tissue Ulcers. Journal of Biomechanics. 47(2014): 1658-1664. 2014.

Selected Research Publications beyond the Last 5 Years

  • MAK AF. The Apparent Viscoelastic Behavior of Articular Cartilage: The Contributions from the Intrinsic Matrix Viscoelasticity and Interstitial Fluid Flows. Journal of Biomechanical Engineering, Trans. ASME, vol. 108, pp. 123-130, 1986.
  • MAK AF, LAI WM and MOW VC. Biphasic Indentation of Articular Cartilage. Part I: Theoretical Analysis. Journal of Biomechanics, vol.20, pp703-714, 1987.
  • KOO TKK, MAK AFT and LEE YL. Posture Effects on the Seating Interface Biomechanics: Comparison between the Roho and Polyurethane Foam Cushions. Archives of Physical Medicine and Rehabilitation. Vol 77, No.1, pp 40-47, 1996.
  • ZHENG YP and MAK AFT. An Ultrasound Indentation System for Biomechanical Properties Assessment of Soft Tissues In-Vivo. IEEE Trans on Biomedical Engineering. 43(9): 912-918. 1996.
  • ZHANG M, ZHENG YP, and MAK AFT. Estimating the Effective Young's Modulus of Soft Tissues from Indentation Tests - Nonlinear Finite Element Analysis of Effects of Friction and Large Deformation. Medical Engineering and Physics. Vol 19:512-517. 1997.
  • ZHENG YP, CHOI YKC, WONG K, CHAN S, MAK AFT. Biomechanical Assessment of Plantar Foot Tissue in Diabetic Patients Using an Ultrasound Indentation System. Ultrasound in Med & Biol. 26:451-456, 2000.
  • KOO TKK and MAK AFT. Feasibility of Using EMG Driven Neuromusculoskeletal Model for Prediction of Dynamic Movement. J Electromyography & Kinesiology. 15: 12-26. Feb 2005.
  • SHUM AWT, LI Jiashen and MAK AFT. Fabrication and Structural Characterization of Porous Biodegradable LGA Scaffolds with Controllable Ranges of Pore Sizes. Polymer Degradation and Stability. 87: 487-493. 2005.
  • LI ZY, LEUNG JYS, TAM EWC, MAK AFT. Wavelet Analysis of Skin Blood Oscillations in Spinal Cord Injured and Able-Bodied Subjects. Arch Phys Med Rehabil. 87:1207-1212, 2006.
  • CHEN Y, MAK AFT, M WANG, LI J, WONG MS. PLLA Scaffolds with Biomimetic Apatite Coating and Biomimetic Apatite/Collagen Composite Coating to Enhance Osteoblast-like Cells Attachment and Activity. Surface and Coatings Technology. Vol201 (3): 575-580. 2006.
  • LI Jiashen, NEAUSSART Audrey, CHEN Yun, MAK AFT. Transfer of Apatite Coating from Porogens to Scaffolds: Uniform Apatite Coating within Porous Poly (Lactide-co-glycolide) Scaffold. J Biomedical Materials Research (Part-A). 80A (1): 226-233. January 2007.
  • CHEN Y, MAK AFT, WANG M, LI JS, WONG MS. In-vitro Behavior of Osteoblast-like Cells on PLLA Films with Biomimetic Apatite/ Collagen Composite Coating. Journal of Materials Science: Materials in Medicine. 19:2261-2268. June 2008.
  • SIU PM, TAM EW, TENG BT, PEI XM, NG JW, BENZI IF, MAK AF. Muscle Apoptosis is Induced in Pressure-Induced Deep Tissue Injury. Journal of Applied Physiology. 107: 1266-1275. 2009.
  • MAK AFT, ZHANG M, TAM EWC. Biomechanics of Pressure Ulcer in Body Tissues Interacting with External Forces during Locomotion. Annual Review of Biomedical Engineering. Vol 12: 29-53. 2010.
  • LI Jiashen, CHEN Yun, MAK AFT, TUAN Rocky, LI Lin, LI Yi. A One-Step Method to Fabricate PLLA Scaffolds with Deposition of Bioactive Hydroxyapatite and Collagen using Ice-based Microporogens. Acta Biomaterialia. 6(6): 2013-2019. June, 2010.

Updated on 13 July 2017