Microfluidics Innovated
Bio-applications

Patents and Invention Disclosures

  1. L. Li, W. Liu, S. Zhong, F. Qu, C. Cheng, Y. P. Ho, "Production of Barcode Beads and Related Systems," 2025 (US Provisional Patent, Application No. 63/745,653).

  2. L. Li, W. Liu, S. Zhong, F. Qu, Y. P. Ho, "A Hydrogel Bead-based Full-Length Single-Cell RNA Sequencing Platform," 2025 (US Provisional Patent, Application No. 63/708,273).

  3. J. Yu, G. Wang, F. Qu, L. Zhao, L. Li, Y. P. Ho, "Methods and Compositions for Nucleic Acid Analysis," 2022 (US Provisional Patent, Application No. 63/424,809).

  4. G. Cheng, Y. P. Ho, "Methods and Apparatus for The Trapping And Rapid Light-driven Selective Release of Droplets," 2022 (US Provisional Patent, Application No. 63/413,933).

  5. F. Qu, L. Zhao, L. Li, Y. P. Ho, "Controllable Dual-Core Merging in Double Emulsions," 2020 (US Provisional Patent, Application No. 63/070,030).

  6. H. F. Chan, Y. W. Lee, Y. K. Ng, Y. P. Ho, "Automatic Micromilling Platform for Microfluidic Devices," 2019 (US Provisional Patent, Application No. 62/896,180; PCT/CN2020/110716).

  7. G. Cheng, S. Beyer, H. P. Ho, T. Ngai, K. T. Lin, Y. P. Ho, "Light-mediated Manipulation of Droplets Stabilized by Fluorinated Nanoparticles with Photothermal Effect," 2019 (US Provisional Patent, Application No. 62/892,101, PCT/CN2020/110715; US Patent No. WO 2021/036967 A1 @ March 4, 2021).

  8. M. H. Rahman, M. K. Chan, M. M. M. Lee, C. H. N. Wong, and Y. P. Ho, "Systems and Methods for Controlled Membrane Disruption Field," 2018 (US Provisional Patent, Application No. 62/832,638; PCT/CN2020/084117; US Patent No. WO 2020/207456 @ June 2, 2022).

  9. M. Stougaard, B. R. Knudsen, M. S. Hede, Y. P. Ho, "Detection of Endonuclease Activity," 2018 (International Application No. PA 2018 70196; PCT/EP2019/058478; US Patent No. 11,530,456 B2 @ Dec. 20, 2022).

  10. M. Stougaard, B. R. Knudsen, M. S. Hede, J. Thomsen, Y. P. Ho, "Methods of Identifying Enzymes and Microorganisms," 2014 (PCT/EP2015/060798; US Patent No. WO 2015/173415 A1 @ May 15, 2015).

  11. Y. P. Ho, B. R. Knudsen et al., "Enzyme Activity Detection by Stepwise Hybridization Of Labeled Entities (SHOFLE)," 2014 (UK Patent Application).

  12. Y. P. Ho, I. Batinic-Haberle, A. Tovmasyan, E. Roberts, K. W. Leong, "Sustained Intratumoral Release, from The Microparticles, of the Therapeutic Strategy Based on Coupling of Two Redox-Active Agents Resulting in Cytotoxic Hydrogen Peroxide Formation," 2013 (Invention Disclosure).

  13. Y. P. Ho, C. L. Grigsby, K. W. Leong, "Microfluidics Assisted Synthesis of Gene Loaded Nanocomplexes," 2011 (Invention Disclosure).

  14. Y. P. Ho, K. W. Leong, S. Juul, J. Koch, M. Stougaard, F. F. Andersen, B. R. Knudsen, "Enzyme Detection by Microfluidics,", 2014 (PCT/DK2012/050327; US Patent No. US 2015/0018228 A1 @ Jan. 15, 2015).

  15. T. H. Wang and Y. P. Ho, "Fluorescence Self-amplification Facilitated by Molecular Nanoprobes and Micro Concentration Devices for Rapid and Ultrasensitive Biological Detection," 2004 (Invention Disclosure).